running Yosemite 10.10.3 Public Beta
problem started after installing Office for Mac 2016 Preview
Seen this same problem in other posts. Able to easily duplicate failures. OneDrive takes up all CPU resources until cache folder in Office 15 folder is trash canned. Problem starts again if OneDrive is shutdown and relaunched second time.
Able to offer Microsoft Support any assistance to help fix problem by submitting logs, screenshots, etc.
Reinstalled fresh OS, same problem as soon as Office Preview is installed.